4l1r
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l1r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l1r RCSB], [http://www.ebi.ac.uk/pdbsum/4l1r PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l1r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l1r RCSB], [http://www.ebi.ac.uk/pdbsum/4l1r PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GB_HHV1K GB_HHV1K]] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding of gD to one of its receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).<ref>PMID:17299053</ref> | ||
==See Also== | ==See Also== | ||
*[[Glycoproteins B and D|Glycoproteins B and D]] | *[[Glycoproteins B and D|Glycoproteins B and D]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 13:39, 24 December 2014
Glycoprotein B from Herpes Simplex Virus type 1, A549T Rate-of-Entry mutant, low-pH
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