2fmx

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fmx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FMX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fmx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FMX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fa9|2fa9]], [[1f6b|1f6b]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fa9|2fa9]], [[1f6b|1f6b]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fmx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fmx RCSB], [http://www.ebi.ac.uk/pdbsum/2fmx PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fmx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fmx RCSB], [http://www.ebi.ac.uk/pdbsum/2fmx PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SAR1B_CRIGR SAR1B_CRIGR]] Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.<ref>PMID:8138575</ref> <ref>PMID:11149932</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Cricetulus griseus]]
[[Category: Cricetulus griseus]]
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[[Category: Bian, C.]]
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[[Category: Bian, C]]
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[[Category: Huang, M.]]
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[[Category: Huang, M]]
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[[Category: Li, Y.]]
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[[Category: Li, Y]]
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[[Category: Rao, Y.]]
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[[Category: Rao, Y]]
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[[Category: Yuan, C.]]
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[[Category: Yuan, C]]
[[Category: Cop ii assembly]]
[[Category: Cop ii assembly]]
[[Category: Dimerization]]
[[Category: Dimerization]]
[[Category: Protein transport]]
[[Category: Protein transport]]
[[Category: Sar1]]
[[Category: Sar1]]

Revision as of 13:40, 24 December 2014

An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)

2fmx, resolution 1.82Å

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