4cot
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4cot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4COT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4COT FirstGlance]. <br> | <table><tr><td colspan='2'>[[4cot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4COT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4COT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arabinan_endo-1,5-alpha-L-arabinosidase Arabinan endo-1,5-alpha-L-arabinosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.99 3.2.1.99] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arabinan_endo-1,5-alpha-L-arabinosidase Arabinan endo-1,5-alpha-L-arabinosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.99 3.2.1.99] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cot RCSB], [http://www.ebi.ac.uk/pdbsum/4cot PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cot RCSB], [http://www.ebi.ac.uk/pdbsum/4cot PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/EABN2_BACSU EABN2_BACSU]] Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1,5-L-arabinan to produce arabino-oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan, and pectin from apple.<ref>PMID:18408032</ref> <ref>PMID:20883454</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The importance of the Abn2 calcium cluster in the endo-1,5-arabinanase activity from Bacillus subtilis.,McVey CE, Ferreira MJ, Correia B, Lahiri S, de Sanctis D, Carrondo MA, Lindley PF, de Sa Nogueira I, Soares CM, Bento I J Biol Inorg Chem. 2014 Feb 19. PMID:24549757<ref>PMID:24549757</ref> | The importance of the Abn2 calcium cluster in the endo-1,5-arabinanase activity from Bacillus subtilis.,McVey CE, Ferreira MJ, Correia B, Lahiri S, de Sanctis D, Carrondo MA, Lindley PF, de Sa Nogueira I, Soares CM, Bento I J Biol Inorg Chem. 2014 Feb 19. PMID:24549757<ref>PMID:24549757</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Arabinan endo-1,5-alpha-L-arabinosidase]] | [[Category: Arabinan endo-1,5-alpha-L-arabinosidase]] | ||
[[Category: Bacsu]] | [[Category: Bacsu]] | ||
| - | [[Category: Bento, I | + | [[Category: Bento, I]] |
| - | [[Category: Carrondo, M A | + | [[Category: Carrondo, M A]] |
| - | [[Category: Correia, B | + | [[Category: Correia, B]] |
| - | [[Category: Ferreira, M J | + | [[Category: Ferreira, M J]] |
| - | [[Category: Lahiri, S | + | [[Category: Lahiri, S]] |
| - | [[Category: Lindley, P F | + | [[Category: Lindley, P F]] |
| - | [[Category: McVey, C E | + | [[Category: McVey, C E]] |
| - | [[Category: Sa-Nogueira, I de | + | [[Category: Sa-Nogueira, I de]] |
| - | [[Category: Soares, C M | + | [[Category: Soares, C M]] |
| - | [[Category: DeSanctis, D | + | [[Category: DeSanctis, D]] |
[[Category: Catalytic mechanism]] | [[Category: Catalytic mechanism]] | ||
[[Category: Endo-alpha-l-arabinananase gh43]] | [[Category: Endo-alpha-l-arabinananase gh43]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Mutagenesis]] | [[Category: Mutagenesis]] | ||
Revision as of 14:17, 24 December 2014
The importance of the Abn2 calcium cluster in the endo-1,5- arabinanase activity from Bacillus subtilis
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