4k4d
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4k4d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K4D FirstGlance]. <br> | <table><tr><td colspan='2'>[[4k4d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K4D FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HFQ:2,4-DIHYDROXYPHENACYL+COENZYME+A'>HFQ</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HFQ:2,4-DIHYDROXYPHENACYL+COENZYME+A'>HFQ</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vh9|1vh9]], [[4k49|4k49]], [[4k4a|4k4a]], [[4k4b|4k4b]], [[4k4c|4k4c]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vh9|1vh9]], [[4k49|4k49]], [[4k4a|4k4a]], [[4k4b|4k4b]], [[4k4c|4k4c]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k4d RCSB], [http://www.ebi.ac.uk/pdbsum/4k4d PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k4d RCSB], [http://www.ebi.ac.uk/pdbsum/4k4d PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ENTH_ECOLI ENTH_ECOLI]] Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Displays esterase activity toward a wide range of substrates, including acyl-CoAs and aryl-CoAs.<ref>PMID:15808744</ref> <ref>PMID:17675380</ref> <ref>PMID:19119850</ref> <ref>PMID:19193103</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Allen, K N | + | [[Category: Allen, K N]] |
| - | [[Category: Dunaway-Mariano, D | + | [[Category: Dunaway-Mariano, D]] |
| - | [[Category: Farelli, J D | + | [[Category: Farelli, J D]] |
| - | [[Category: Ru, W | + | [[Category: Ru, W]] |
[[Category: Hotdog fold]] | [[Category: Hotdog fold]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Thioeatsrase]] | [[Category: Thioeatsrase]] | ||
Revision as of 14:26, 24 December 2014
X-ray crystal structure of E. coli YbdB complexed with 2,4-dihydroxyphenacyl-CoA
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