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3cyi
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cyi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cyi RCSB], [http://www.ebi.ac.uk/pdbsum/3cyi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cyi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cyi RCSB], [http://www.ebi.ac.uk/pdbsum/3cyi PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRXN1_HUMAN SRXN1_HUMAN]] Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.<ref>PMID:15448164</ref> <ref>PMID:15590625</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Sulfiredoxin]] | [[Category: Sulfiredoxin]] | ||
| - | [[Category: Johnson, L C | + | [[Category: Johnson, L C]] |
[[Category: Jonsson, T J]] | [[Category: Jonsson, T J]] | ||
| - | [[Category: Lowther, W T | + | [[Category: Lowther, W T]] |
| - | [[Category: Murray, M S | + | [[Category: Murray, M S]] |
[[Category: Antioxidant]] | [[Category: Antioxidant]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
Revision as of 14:27, 24 December 2014
Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ATP:Mg2+
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