1z68

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z68]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z68 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z68]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z68 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z68 RCSB], [http://www.ebi.ac.uk/pdbsum/1z68 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z68 RCSB], [http://www.ebi.ac.uk/pdbsum/1z68 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SEPR_HUMAN SEPR_HUMAN]] In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.<ref>PMID:16651416</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aertgeerts, K.]]
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[[Category: Aertgeerts, K]]
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[[Category: Kraus, M L.]]
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[[Category: Kraus, M L]]
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[[Category: Levin, I.]]
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[[Category: Levin, I]]
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[[Category: Prasad, G S.]]
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[[Category: Prasad, G S]]
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[[Category: Salakian, S.]]
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[[Category: Salakian, S]]
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[[Category: Shi, L.]]
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[[Category: Shi, L]]
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[[Category: Snell, G P.]]
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[[Category: Snell, G P]]
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[[Category: Sridhar, V.]]
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[[Category: Sridhar, V]]
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[[Category: Tennant, M G.]]
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[[Category: Tennant, M G]]
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[[Category: Wijnands, R.]]
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[[Category: Wijnands, R]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang, Y]]
[[Category: Dipeptidylpeptidase]]
[[Category: Dipeptidylpeptidase]]
[[Category: Fapalpha]]
[[Category: Fapalpha]]

Revision as of 14:35, 24 December 2014

Crystal Structure Of Human Fibroblast Activation Protein alpha

1z68, resolution 2.60Å

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