3ssx
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ssx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SSX FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ssx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SSX FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ssw|3ssw]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ssw|3ssw]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b4393, JW4356, rtrY, trpR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b4393, JW4356, rtrY, trpR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ssx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ssx RCSB], [http://www.ebi.ac.uk/pdbsum/3ssx PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ssx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ssx RCSB], [http://www.ebi.ac.uk/pdbsum/3ssx PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Environment-dependent long-range structural distortion in a temperature-sensitive point mutant.,Carey J, Benoff B, Harish B, Yuan L, Lawson CL Protein Sci. 2011 Nov 4. doi: 10.1002/pro.759. PMID:22057811<ref>PMID:22057811</ref> | Environment-dependent long-range structural distortion in a temperature-sensitive point mutant.,Carey J, Benoff B, Harish B, Yuan L, Lawson CL Protein Sci. 2011 Nov 4. doi: 10.1002/pro.759. PMID:22057811<ref>PMID:22057811</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Benoff, B | + | [[Category: Benoff, B]] |
| - | [[Category: Berman, H M | + | [[Category: Berman, H M]] |
| - | [[Category: Carey, J | + | [[Category: Carey, J]] |
| - | [[Category: Lawson, C L | + | [[Category: Lawson, C L]] |
[[Category: Dna binding]] | [[Category: Dna binding]] | ||
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Helix-turn-helix motif]] | [[Category: Helix-turn-helix motif]] | ||
[[Category: Trp operator]] | [[Category: Trp operator]] | ||
Revision as of 14:38, 24 December 2014
E. coli trp aporeporessor L75F mutant
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