1wi8

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wi8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WI8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wi8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WI8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA adSE02039 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA adSE02039 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1wi8 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wi8 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1wi8 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wi8 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IF4B_HUMAN IF4B_HUMAN]] Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Muto, Y.]]
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[[Category: Muto, Y]]
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[[Category: Nagata, T.]]
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[[Category: Nagata, T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu, M]]
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[[Category: Suzuki, S.]]
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[[Category: Suzuki, S]]
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[[Category: Terada, T.]]
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[[Category: Terada, T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Biosynthetic protein]]
[[Category: Biosynthetic protein]]
[[Category: Rbd]]
[[Category: Rbd]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rna binding domain]]
[[Category: Rna binding domain]]
[[Category: Rna recognition motif]]
[[Category: Rna recognition motif]]
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[[Category: Rrm]]
[[Category: Rrm]]
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 

Revision as of 14:54, 24 December 2014

Solution structure of the RNA binding domain of eukaryotic initiation factor 4B

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