2ywc

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ywc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ywc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ywb|2ywb]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ywb|2ywb]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywc RCSB], [http://www.ebi.ac.uk/pdbsum/2ywc PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywc TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywc RCSB], [http://www.ebi.ac.uk/pdbsum/2ywc PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywc TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GUAA_THET8 GUAA_THET8]] Catalyzes the synthesis of GMP from XMP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Baba, S.]]
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[[Category: Baba, S]]
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[[Category: Kanagawa, M.]]
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[[Category: Kanagawa, M]]
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[[Category: Kawai, G.]]
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[[Category: Kawai, G]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sampei, G.]]
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[[Category: Sampei, G]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Atp binding]]
[[Category: Atp binding]]
[[Category: Gmp synthetase]]
[[Category: Gmp synthetase]]
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[[Category: Nppsfa]]
[[Category: Nppsfa]]
[[Category: Purine nucleotide biosynthetic pathway]]
[[Category: Purine nucleotide biosynthetic pathway]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Xmp binding]]
[[Category: Xmp binding]]

Revision as of 14:56, 24 December 2014

Crystal structure of GMP synthetase from Thermus thermophilus in complex with XMP

2ywc, resolution 2.20Å

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