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4dn8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4dn8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DN8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4dn8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DN8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SFTPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SFTPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dn8 RCSB], [http://www.ebi.ac.uk/pdbsum/4dn8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dn8 RCSB], [http://www.ebi.ac.uk/pdbsum/4dn8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SFTPD_PIG SFTPD_PIG]] Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Cafarella, T M | + | [[Category: Cafarella, T M]] |
| - | [[Category: Crouch, E C | + | [[Category: Crouch, E C]] |
| - | [[Category: Eijk, M van | + | [[Category: Eijk, M van]] |
| - | [[Category: Haagsman, H P | + | [[Category: Haagsman, H P]] |
| - | [[Category: Hartshorn, K L | + | [[Category: Hartshorn, K L]] |
| - | [[Category: Head, J F | + | [[Category: Head, J F]] |
| - | [[Category: Luo, D | + | [[Category: Luo, D]] |
| - | [[Category: Rynkiewicz, M J | + | [[Category: Rynkiewicz, M J]] |
| - | [[Category: Schulten, K | + | [[Category: Schulten, K]] |
| - | [[Category: Seaton, B A | + | [[Category: Seaton, B A]] |
| - | [[Category: White, M R | + | [[Category: White, M R]] |
| - | [[Category: Zou, X | + | [[Category: Zou, X]] |
[[Category: Carbohydrate/sugar binding]] | [[Category: Carbohydrate/sugar binding]] | ||
[[Category: Collectin]] | [[Category: Collectin]] | ||
Revision as of 14:57, 24 December 2014
Structure of porcine surfactant protein D neck and carbohydrate recognition domain complexed with mannose
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