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3j7a
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3j7a]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J7A FirstGlance]. <br> | <table><tr><td colspan='2'>[[3j7a]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J7A FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34G:EMETINE'>34G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34G:EMETINE'>34G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j79|3j79]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j79|3j79]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j7a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j7a RCSB], [http://www.ebi.ac.uk/pdbsum/3j7a PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j7a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j7a RCSB], [http://www.ebi.ac.uk/pdbsum/3j7a PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RSSA_PLAF7 RSSA_PLAF7]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: Bai, X C | + | [[Category: Bai, X C]] |
| - | [[Category: Baum, J | + | [[Category: Baum, J]] |
| - | [[Category: Brown, A | + | [[Category: Brown, A]] |
| - | [[Category: Condron, M | + | [[Category: Condron, M]] |
| - | [[Category: Fernandez, I S | + | [[Category: Fernandez, I S]] |
| - | [[Category: Hanssen, E | + | [[Category: Hanssen, E]] |
| - | [[Category: Scheres, S H.W | + | [[Category: Scheres, S H.W]] |
| - | [[Category: Tan, Y H | + | [[Category: Tan, Y H]] |
| - | [[Category: Wong, W | + | [[Category: Wong, W]] |
[[Category: Emetine]] | [[Category: Emetine]] | ||
[[Category: Ribosome-inhibitor complex]] | [[Category: Ribosome-inhibitor complex]] | ||
Revision as of 15:02, 24 December 2014
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
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