2yx5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yx5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YX5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YX5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yx5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YX5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YX5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yx5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yx5 RCSB], [http://www.ebi.ac.uk/pdbsum/2yx5 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yx5 TOPSAN]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yx5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yx5 RCSB], [http://www.ebi.ac.uk/pdbsum/2yx5 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yx5 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Y1593_METJA Y1593_METJA]] Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Agari, Y.]]
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[[Category: Agari, Y]]
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[[Category: Baba, S.]]
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[[Category: Baba, S]]
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[[Category: Chen, L Q.]]
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[[Category: Chen, L Q]]
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[[Category: Chrzas, J.]]
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[[Category: Chrzas, J]]
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[[Category: Fu, Z Q.]]
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[[Category: Fu, Z Q]]
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[[Category: Kanagawa, M.]]
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[[Category: Kanagawa, M]]
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[[Category: Kawai, G.]]
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[[Category: Kawai, G]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sampei, G.]]
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[[Category: Sampei, G]]
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[[Category: Wang, B C.]]
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[[Category: Wang, B C]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Anti parallel beta sheet]]
[[Category: Anti parallel beta sheet]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Unknown function]]
[[Category: Unknown function]]

Revision as of 15:18, 24 December 2014

Crystal Structure of Methanocaldococcus jannaschii PurS, One of the Subunits of Formylglycinamide Ribonucleotide Amidotransferase in the Purine Biosynthetic Pathway

2yx5, resolution 2.30Å

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