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4e19
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== |
| + | <StructureSection load='4e19' size='340' side='right' caption='[[4e19]], [[Resolution|resolution]] 1.41Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4e19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E19 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VNG_0255C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64091 Halobacterium sp. NRC-1])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e19 RCSB], [http://www.ebi.ac.uk/pdbsum/4e19 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA]] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonuclease|Ribonuclease]] | |
| - | + | *[[Temp|Temp]] | |
| - | + | *[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Halobacterium sp. nrc-1]] | [[Category: Halobacterium sp. nrc-1]] | ||
[[Category: Ribonuclease H]] | [[Category: Ribonuclease H]] | ||
| - | [[Category: Angkawidjaja, C | + | [[Category: Angkawidjaja, C]] |
| - | [[Category: Kanaya, S | + | [[Category: Kanaya, S]] |
| - | [[Category: Koga, Y | + | [[Category: Koga, Y]] |
| - | [[Category: You, D J | + | [[Category: You, D J]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Rnase h1]] | [[Category: Rnase h1]] | ||
Revision as of 15:19, 24 December 2014
Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
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