3bsb

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bsb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BSB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bsb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BSB FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m8y|1m8y]], [[1m8x|1m8x]], [[1m8w|1m8w]], [[3bsx|3bsx]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m8y|1m8y]], [[1m8x|1m8x]], [[1m8w|1m8w]], [[3bsx|3bsx]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PUM1, KIAA0099, PUMH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PUM1, KIAA0099, PUMH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bsb RCSB], [http://www.ebi.ac.uk/pdbsum/3bsb PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bsb RCSB], [http://www.ebi.ac.uk/pdbsum/3bsb PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aggarwal, A K.]]
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[[Category: Aggarwal, A K]]
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[[Category: Gupta, Y K.]]
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[[Category: Gupta, Y K]]
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[[Category: Nair, D T.]]
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[[Category: Nair, D T]]
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[[Category: Wharton, R P.]]
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[[Category: Wharton, R P]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]

Revision as of 15:20, 24 December 2014

Crystal Structure of Human Pumilio1 in Complex with CyclinB reverse RNA

3bsb, resolution 2.80Å

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