2l9r
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l9r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l9r RCSB], [http://www.ebi.ac.uk/pdbsum/2l9r PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l9r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l9r RCSB], [http://www.ebi.ac.uk/pdbsum/2l9r PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NKX31_HUMAN NKX31_HUMAN]] Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.<ref>PMID:19462257</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 15:21, 24 December 2014
Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A
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