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2xer
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xer OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xer RCSB], [http://www.ebi.ac.uk/pdbsum/2xer PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xer OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xer RCSB], [http://www.ebi.ac.uk/pdbsum/2xer PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PATL1_HUMAN PATL1_HUMAN]] RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).<ref>PMID:17936923</ref> <ref>PMID:19628699</ref> <ref>PMID:20584987</ref> <ref>PMID:20852261</ref> <ref>PMID:20543818</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 15:27, 24 December 2014
HUMAN PATL1 C-TERMINAL DOMAIN (LOOP VARIANT WITH SULFATES)
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