4q33
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4q33]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q33 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4q33]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q33 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YA:4-[(1R)-1-[1-(4-CHLOROPHENYL)-1,2,3-TRIAZOL-4-YL]ETHOXY]-1-OXIDANYL-QUINOLINE'>2YA</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YA:4-[(1R)-1-[1-(4-CHLOROPHENYL)-1,2,3-TRIAZOL-4-YL]ETHOXY]-1-OXIDANYL-QUINOLINE'>2YA</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q32|4q32]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q32|4q32]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q33 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q33 RCSB], [http://www.ebi.ac.uk/pdbsum/4q33 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q33 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q33 RCSB], [http://www.ebi.ac.uk/pdbsum/4q33 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q0TN42_CLOP1 Q0TN42_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: IMP dehydrogenase]] | [[Category: IMP dehydrogenase]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Gollapalli, D R | + | [[Category: Gollapalli, D R]] |
| - | [[Category: Gorla, S K | + | [[Category: Gorla, S K]] |
| - | [[Category: Gu, M | + | [[Category: Gu, M]] |
| - | [[Category: Hedstrom, L | + | [[Category: Hedstrom, L]] |
| - | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Kim, Y | + | [[Category: Kim, Y]] |
| - | [[Category: Makowska-Grzyska, M | + | [[Category: Makowska-Grzyska, M]] |
| - | [[Category: Maltseva, N | + | [[Category: Maltseva, N]] |
| - | [[Category: Mandapati, K | + | [[Category: Mandapati, K]] |
| - | [[Category: Mulligan, R | + | [[Category: Mulligan, R]] |
| - | [[Category: Zhang, M | + | [[Category: Zhang, M]] |
| - | + | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Dehydrogenase]] | [[Category: Dehydrogenase]] | ||
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[[Category: Niaid]] | [[Category: Niaid]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Tim barrel]] | [[Category: Tim barrel]] | ||
Revision as of 15:32, 24 December 2014
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110
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Categories: IMP dehydrogenase | Anderson, W F | Structural genomic | Gollapalli, D R | Gorla, S K | Gu, M | Hedstrom, L | Joachimiak, A | Kim, Y | Makowska-Grzyska, M | Maltseva, N | Mandapati, K | Mulligan, R | Zhang, M | Csgid | Dehydrogenase | National institute of allergy and infectious disease | Niaid | Oxidoreductase | Tim barrel
