1xnr

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[[Image:1xnr.gif|left|200px]]<br /><applet load="1xnr" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1xnr.gif|left|200px]]
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caption="1xnr, resolution 3.10&Aring;" />
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'''Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center'''<br />
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{{Structure
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|PDB= 1xnr |SIZE=350|CAPTION= <scene name='initialview01'>1xnr</scene>, resolution 3.10&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=PAR:PAROMOMYCIN'>PAR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1XNR is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PAR:'>PAR</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNR OCA].
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1XNR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNR OCA].
==Reference==
==Reference==
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Structure of a purine-purine wobble base pair in the decoding center of the ribosome., Murphy FV 4th, Ramakrishnan V, Nat Struct Mol Biol. 2004 Dec;11(12):1251-2. Epub 2004 Nov 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15558050 15558050]
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Structure of a purine-purine wobble base pair in the decoding center of the ribosome., Murphy FV 4th, Ramakrishnan V, Nat Struct Mol Biol. 2004 Dec;11(12):1251-2. Epub 2004 Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15558050 15558050]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: PAR]]
[[Category: PAR]]
[[Category: ZN]]
[[Category: ZN]]
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[[Category: 30s]]
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[[Category: 30]]
[[Category: decoding]]
[[Category: decoding]]
[[Category: ribosome]]
[[Category: ribosome]]
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[[Category: trna modification]]
[[Category: trna modification]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:56:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:12:16 2008''

Revision as of 13:12, 20 March 2008

Image:1xnr.gif


PDB ID 1xnr

Drag the structure with the mouse to rotate
, resolution 3.10Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center


Overview

Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position.

About this Structure

1XNR is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of a purine-purine wobble base pair in the decoding center of the ribosome., Murphy FV 4th, Ramakrishnan V, Nat Struct Mol Biol. 2004 Dec;11(12):1251-2. Epub 2004 Nov 21. PMID:15558050

Page seeded by OCA on Thu Mar 20 15:12:16 2008

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OCA

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