1m44

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1m44]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M44 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1m44]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M44 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m4d|1m4d]], [[1m4g|1m4g]], [[1m4i|1m4i]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m4d|1m4d]], [[1m4g|1m4g]], [[1m4i|1m4i]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m44 RCSB], [http://www.ebi.ac.uk/pdbsum/1m44 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m44 RCSB], [http://www.ebi.ac.uk/pdbsum/1m44 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AAC2_MYCTU AAC2_MYCTU]] Catalyzes the coenzyme A-dependent acetylation of the 2' hydroxyl or amino group of a broad spectrum of aminoglycosides. It confers resistance to aminoglycosides.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Blanchard, J S.]]
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[[Category: Blanchard, J S]]
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[[Category: Hegde, S S.]]
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[[Category: Hegde, S S]]
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[[Category: Javid-Majd, F.]]
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[[Category: Javid-Majd, F]]
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[[Category: Roderick, S L.]]
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[[Category: Roderick, S L]]
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[[Category: Vetting, M W.]]
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[[Category: Vetting, M W]]
[[Category: Coa binding motif]]
[[Category: Coa binding motif]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 15:44, 24 December 2014

Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-APO Structure

1m44, resolution 1.60Å

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