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1kig
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1kig]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Ornithodoros_moubata Ornithodoros moubata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KIG FirstGlance]. <br> | <table><tr><td colspan='2'>[[1kig]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Ornithodoros_moubata Ornithodoros moubata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KIG FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] </span></td></tr> | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kig OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kig RCSB], [http://www.ebi.ac.uk/pdbsum/1kig PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kig OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kig RCSB], [http://www.ebi.ac.uk/pdbsum/1kig PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FA10_BOVIN FA10_BOVIN]] Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. [[http://www.uniprot.org/uniprot/TAP_ORNMO TAP_ORNMO]] TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Ornithodoros moubata]] | [[Category: Ornithodoros moubata]] | ||
| - | [[Category: Alexander, R | + | [[Category: Alexander, R]] |
| - | [[Category: Chang, C H | + | [[Category: Chang, C H]] |
| - | [[Category: Wei, A | + | [[Category: Wei, A]] |
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Plasma]] | [[Category: Plasma]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 15:44, 24 December 2014
BOVINE FACTOR XA
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