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3fai

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fai]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FAI FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fai]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FAI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x8g|1x8g]], [[1x8h|1x8h]], [[1x8i|1x8i]], [[2gkl|2gkl]], [[2qds|2qds]], [[3f9o|3f9o]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x8g|1x8g]], [[1x8h|1x8h]], [[1x8i|1x8i]], [[2gkl|2gkl]], [[2qds|2qds]], [[3f9o|3f9o]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 Aeromonas hydrophila])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 Aeromonas hydrophila])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fai OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fai RCSB], [http://www.ebi.ac.uk/pdbsum/3fai PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fai FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fai OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fai RCSB], [http://www.ebi.ac.uk/pdbsum/3fai PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BLAB_AERHY BLAB_AERHY]] Can hydrolyze carbapenem compounds.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Aeromonas hydrophila]]
[[Category: Aeromonas hydrophila]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: Delbruck, H.]]
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[[Category: Delbruck, H]]
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[[Category: Hoffmann, K M.V.]]
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[[Category: Hoffmann, K M.V]]
[[Category: Antibiotic resistance]]
[[Category: Antibiotic resistance]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]

Revision as of 15:50, 24 December 2014

The Di Zinc Carbapenemase CphA N220G mutant

3fai, resolution 1.70Å

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