3zyw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zyw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZYW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zyw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZYW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yan|2yan]], [[2wz9|2wz9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yan|2yan]], [[2wz9|2wz9]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zyw RCSB], [http://www.ebi.ac.uk/pdbsum/3zyw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zyw RCSB], [http://www.ebi.ac.uk/pdbsum/3zyw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GLRX3_HUMAN GLRX3_HUMAN]] Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Cocking, R.]]
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[[Category: Cocking, R]]
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[[Category: Delft, F Von.]]
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[[Category: Delft, F Von]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Johansson, C.]]
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[[Category: Johansson, C]]
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[[Category: Kavanagh, K L.]]
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[[Category: Kavanagh, K L]]
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[[Category: Krojer, T.]]
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[[Category: Krojer, T]]
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[[Category: Muniz, J R.C.]]
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[[Category: Muniz, J R.C]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann, U]]
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[[Category: Vollmar, M.]]
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[[Category: Vollmar, M]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Metal binding protein]]
[[Category: Metal binding protein]]

Revision as of 15:59, 24 December 2014

Crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (GLRX3)

3zyw, resolution 1.84Å

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