1xru

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xru]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XRU FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xru]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XRU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kduI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kduI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-deoxy-L-threo-5-hexosulose-uronate_ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.17 5.3.1.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-deoxy-L-threo-5-hexosulose-uronate_ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.17 5.3.1.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xru OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xru RCSB], [http://www.ebi.ac.uk/pdbsum/1xru PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xru OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xru RCSB], [http://www.ebi.ac.uk/pdbsum/1xru PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KDUI_ECOLI KDUI_ECOLI]] Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity).[HAMAP-Rule:MF_00687]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase]]
[[Category: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Crowther, R L.]]
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[[Category: Crowther, R L]]
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[[Category: Georgiadis, M M.]]
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[[Category: Georgiadis, M M]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Cupin]]
[[Category: Cupin]]
[[Category: Isomerase]]
[[Category: Isomerase]]

Revision as of 16:00, 24 December 2014

Crystal Structure of 5-keto-4-deoxyuronate Isomerase from Eschericia coli

1xru, resolution 1.94Å

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