2ist

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ist]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IST FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ist]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IST FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qyu|1qyu]], [[1prz|1prz]], [[1v9f|1v9f]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qyu|1qyu]], [[1prz|1prz]], [[1v9f|1v9f]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rluD, sfhB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rluD, sfhB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ist FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ist OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ist RCSB], [http://www.ebi.ac.uk/pdbsum/2ist PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ist FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ist OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ist RCSB], [http://www.ebi.ac.uk/pdbsum/2ist PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RLUD_ECOLI RLUD_ECOLI]] Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit.<ref>PMID:11087118</ref> <ref>PMID:17937767</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[TRNA pseudouridine synthase|TRNA pseudouridine synthase]]
*[[TRNA pseudouridine synthase|TRNA pseudouridine synthase]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Finer-Moore, J S.]]
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[[Category: Finer-Moore, J S]]
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[[Category: Foster, P G.]]
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[[Category: Foster, P G]]
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[[Category: Stroud, R M.]]
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[[Category: Stroud, R M]]
[[Category: Alpha-beta fold]]
[[Category: Alpha-beta fold]]
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Pseudouridine synthase]]
[[Category: Pseudouridine synthase]]
[[Category: S4 domain]]
[[Category: S4 domain]]

Revision as of 16:21, 24 December 2014

crystal structure of RluD from E. coli

2ist, resolution 1.86Å

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