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1htd
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1htd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HTD FirstGlance]. <br> | <table><tr><td colspan='2'>[[1htd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HTD FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Atrolysin_C Atrolysin C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.42 3.4.24.42] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Atrolysin_C Atrolysin C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.42 3.4.24.42] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1htd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1htd RCSB], [http://www.ebi.ac.uk/pdbsum/1htd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1htd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1htd RCSB], [http://www.ebi.ac.uk/pdbsum/1htd PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HRTD_CROAT HRTD_CROAT]] Snake venom zinc metalloproteinase that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins).<ref>PMID:2817904</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Atrolysin C]] | [[Category: Atrolysin C]] | ||
[[Category: Crotalus atrox]] | [[Category: Crotalus atrox]] | ||
| - | [[Category: Blood, C | + | [[Category: Blood, C]] |
| - | [[Category: Bode, W | + | [[Category: Bode, W]] |
| - | [[Category: Botos, I | + | [[Category: Botos, I]] |
| - | [[Category: Doll, R | + | [[Category: Doll, R]] |
| - | [[Category: Fox, J W | + | [[Category: Fox, J W]] |
| - | [[Category: Gomis-Rueth, F X | + | [[Category: Gomis-Rueth, F X]] |
| - | [[Category: Meyer, E F | + | [[Category: Meyer, E F]] |
| - | [[Category: Njoroge, F G | + | [[Category: Njoroge, F G]] |
| - | [[Category: Zhang, D | + | [[Category: Zhang, D]] |
[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
Revision as of 16:27, 24 December 2014
STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN C (HT-D)
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Categories: Atrolysin C | Crotalus atrox | Blood, C | Bode, W | Botos, I | Doll, R | Fox, J W | Gomis-Rueth, F X | Meyer, E F | Njoroge, F G | Zhang, D | Metalloprotease
