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3rvv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3rvv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_farinae Dermatophagoides farinae] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RVV FirstGlance]. <br> | <table><tr><td colspan='2'>[[3rvv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_farinae Dermatophagoides farinae] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RVV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rvt|3rvt]], [[3rvu|3rvu]], [[3rvw|3rvw]], [[3rvx|3rvx]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rvt|3rvt]], [[3rvu|3rvu]], [[3rvw|3rvw]], [[3rvx|3rvx]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rvv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rvv RCSB], [http://www.ebi.ac.uk/pdbsum/3rvv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rvv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rvv RCSB], [http://www.ebi.ac.uk/pdbsum/3rvv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PEPT1_DERFA PEPT1_DERFA]] Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Molecular determinants for antibody binding on group 1 house dust mite allergens.,Chruszcz M, Pomes A, Glesner J, Vailes LD, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-Mills TA, Minor W, Chapman MD J Biol Chem. 2012 Mar 2;287(10):7388-98. Epub 2011 Dec 30. PMID:22210776<ref>PMID:22210776</ref> | Molecular determinants for antibody binding on group 1 house dust mite allergens.,Chruszcz M, Pomes A, Glesner J, Vailes LD, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-Mills TA, Minor W, Chapman MD J Biol Chem. 2012 Mar 2;287(10):7388-98. Epub 2011 Dec 30. PMID:22210776<ref>PMID:22210776</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Dermatophagoides farinae]] | [[Category: Dermatophagoides farinae]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Chapman, M D | + | [[Category: Chapman, M D]] |
| - | [[Category: Chruszcz, M | + | [[Category: Chruszcz, M]] |
| - | [[Category: Minor, W | + | [[Category: Minor, W]] |
| - | [[Category: Pomes, A | + | [[Category: Pomes, A]] |
| - | [[Category: Vailes, L D | + | [[Category: Vailes, L D]] |
[[Category: Complex between an allergen and fab fragment of 4c1 antibody]] | [[Category: Complex between an allergen and fab fragment of 4c1 antibody]] | ||
[[Category: Hydrolase-immune system complex]] | [[Category: Hydrolase-immune system complex]] | ||
Revision as of 16:32, 24 December 2014
Crystal structure of Der f 1 complexed with Fab 4C1
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