2qx5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2qx5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QX5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QX5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2qx5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QX5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QX5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIC96 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIC96 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qx5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qx5 RCSB], [http://www.ebi.ac.uk/pdbsum/2qx5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qx5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qx5 RCSB], [http://www.ebi.ac.uk/pdbsum/2qx5 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NIC96_YEAST NIC96_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NIC96, which is localized to the core of the NPC and the distal ring of the nuclear basket, is required for de novo assembly of NPCs. It is involved in nuclear GSP1 import.<ref>PMID:7828598</ref> <ref>PMID:8682855</ref> <ref>PMID:9017593</ref> <ref>PMID:10428845</ref> <ref>PMID:10617624</ref> <ref>PMID:11121302</ref> <ref>PMID:10806080</ref> <ref>PMID:11689687</ref> <ref>PMID:12403813</ref> <ref>PMID:12496130</ref> <ref>PMID:12730220</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Jeudy, S.]]
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[[Category: Jeudy, S]]
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[[Category: Schwartz, T U.]]
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[[Category: Schwartz, T U]]
[[Category: Mrna transport]]
[[Category: Mrna transport]]
[[Category: Nuclear pore complex]]
[[Category: Nuclear pore complex]]

Revision as of 16:47, 24 December 2014

Structure of nucleoporin Nic96

2qx5, resolution 2.50Å

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