3bhd
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3bhd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BHD FirstGlance]. <br> | <table><tr><td colspan='2'>[[3bhd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BHD FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THTPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THTPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-triphosphatase Thiamine-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.28 3.6.1.28] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-triphosphatase Thiamine-triphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.28 3.6.1.28] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bhd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bhd RCSB], [http://www.ebi.ac.uk/pdbsum/3bhd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bhd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bhd RCSB], [http://www.ebi.ac.uk/pdbsum/3bhd PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/THTPA_HUMAN THTPA_HUMAN]] Hydrolase highly specific for thiamine triphosphate (ThTP). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thiamine-triphosphatase]] | [[Category: Thiamine-triphosphatase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Berg, S Van den | + | [[Category: Berg, S Van den]] |
| - | [[Category: Berglund, H | + | [[Category: Berglund, H]] |
| - | [[Category: Busam, R D | + | [[Category: Busam, R D]] |
| - | [[Category: Collins, R | + | [[Category: Collins, R]] |
| - | [[Category: Dahlgren, L G | + | [[Category: Dahlgren, L G]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Flodin, S | + | [[Category: Flodin, S]] |
| - | [[Category: Flores, A | + | [[Category: Flores, A]] |
| - | [[Category: Graslund, S | + | [[Category: Graslund, S]] |
| - | [[Category: Hallberg, B M | + | [[Category: Hallberg, B M]] |
| - | [[Category: Hammarstrom, M | + | [[Category: Hammarstrom, M]] |
| - | [[Category: Herman, M D | + | [[Category: Herman, M D]] |
| - | [[Category: Johansson, A | + | [[Category: Johansson, A]] |
| - | [[Category: Johansson, I | + | [[Category: Johansson, I]] |
| - | [[Category: Kallas, A | + | [[Category: Kallas, A]] |
| - | [[Category: Karlberg, T | + | [[Category: Karlberg, T]] |
| - | [[Category: Kotenyova, T | + | [[Category: Kotenyova, T]] |
| - | [[Category: Lehtio, L | + | [[Category: Lehtio, L]] |
| - | [[Category: Moche, M | + | [[Category: Moche, M]] |
| - | [[Category: Nilsson, M E | + | [[Category: Nilsson, M E]] |
| - | [[Category: Nordlund, P | + | [[Category: Nordlund, P]] |
| - | [[Category: Nyman, T | + | [[Category: Nyman, T]] |
| - | [[Category: Persson, C | + | [[Category: Persson, C]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sagemark, J | + | [[Category: Sagemark, J]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Svensson, L | + | [[Category: Svensson, L]] |
| - | [[Category: Thorsell, A G | + | [[Category: Thorsell, A G]] |
| - | [[Category: Tresaugues, L | + | [[Category: Tresaugues, L]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Welin, M | + | [[Category: Welin, M]] |
[[Category: Cyth domain]] | [[Category: Cyth domain]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Phosphatase]] | [[Category: Phosphatase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomics consortium]] | ||
Revision as of 16:51, 24 December 2014
Crystal structure of human thiamine triphosphatase (THTPA)
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Categories: Homo sapiens | Thiamine-triphosphatase | Arrowsmith, C H | Berg, S Van den | Berglund, H | Busam, R D | Collins, R | Dahlgren, L G | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hallberg, B M | Hammarstrom, M | Herman, M D | Johansson, A | Johansson, I | Kallas, A | Karlberg, T | Kotenyova, T | Lehtio, L | Moche, M | Nilsson, M E | Nordlund, P | Nyman, T | Persson, C | Structural genomic | Sagemark, J | Sundstrom, M | Svensson, L | Thorsell, A G | Tresaugues, L | Weigelt, J | Welin, M | Cyth domain | Hydrolase | Phosphatase | Sgc
