1y4i

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[[Image:1y4i.gif|left|200px]]<br /><applet load="1y4i" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1y4i.gif|left|200px]]
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caption="1y4i, resolution 1.90&Aring;" />
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'''Crystal structure of Citrobacter Freundii L-methionine-lyase'''<br />
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{{Structure
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|PDB= 1y4i |SIZE=350|CAPTION= <scene name='initialview01'>1y4i</scene>, resolution 1.90&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11]
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|GENE= megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 Citrobacter freundii])
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}}
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'''Crystal structure of Citrobacter Freundii L-methionine-lyase'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1Y4I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y4I OCA].
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1Y4I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y4I OCA].
==Reference==
==Reference==
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Structure of Citrobacter freundii L-methionine gamma-lyase., Mamaeva DV, Morozova EA, Nikulin AD, Revtovich SV, Nikonov SV, Garber MB, Demidkina TV, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt, 6):546-9. Epub 2005 Jun 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16511092 16511092]
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Structure of Citrobacter freundii L-methionine gamma-lyase., Mamaeva DV, Morozova EA, Nikulin AD, Revtovich SV, Nikonov SV, Garber MB, Demidkina TV, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt, 6):546-9. Epub 2005 Jun 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511092 16511092]
[[Category: Citrobacter freundii]]
[[Category: Citrobacter freundii]]
[[Category: Methionine gamma-lyase]]
[[Category: Methionine gamma-lyase]]
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[[Category: pyridoxal-5'-phosphate]]
[[Category: pyridoxal-5'-phosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:01:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:18:20 2008''

Revision as of 13:18, 20 March 2008


PDB ID 1y4i

Drag the structure with the mouse to rotate
, resolution 1.90Å
Ligands:
Gene: megL (Citrobacter freundii)
Activity: Methionine gamma-lyase, with EC number 4.4.1.11
Coordinates: save as pdb, mmCIF, xml



Crystal structure of Citrobacter Freundii L-methionine-lyase


Overview

L-Methionine gamma-lyase (MGL) is a pyridoxal 5'-phosphate (PLP) dependent enzyme that catalyzes gamma-elimination of L-methionine. The crystal structure of MGL from Citrobacter freundii has been determined at 1.9 A resolution. The spatial fold of the protein is similar to those of MGLs from Pseudomonas putida and Trichomonas vaginalis. The comparison of these structures revealed that there are differences in PLP-binding residues and positioning of the surrounding flexible loops.

About this Structure

1Y4I is a Single protein structure of sequence from Citrobacter freundii. Full crystallographic information is available from OCA.

Reference

Structure of Citrobacter freundii L-methionine gamma-lyase., Mamaeva DV, Morozova EA, Nikulin AD, Revtovich SV, Nikonov SV, Garber MB, Demidkina TV, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt, 6):546-9. Epub 2005 Jun 1. PMID:16511092

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