2atp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2atp]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ATP FirstGlance]. <br> | <table><tr><td colspan='2'>[[2atp]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ATP FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bqh|1bqh]], [[1nez|1nez]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bqh|1bqh]], [[1nez|1nez]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), Cd8b, Lyt-3, Lyt3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), Cd8b, Lyt-3, Lyt3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2atp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2atp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2atp RCSB], [http://www.ebi.ac.uk/pdbsum/2atp PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2atp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2atp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2atp RCSB], [http://www.ebi.ac.uk/pdbsum/2atp PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CD8A_MOUSE CD8A_MOUSE]] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. [[http://www.uniprot.org/uniprot/CD8B_MOUSE CD8B_MOUSE]] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Chang, H C | + | [[Category: Chang, H C]] |
| - | [[Category: Le, Y | + | [[Category: Le, Y]] |
| - | [[Category: Liu, J H | + | [[Category: Liu, J H]] |
| - | [[Category: Ouyang, J | + | [[Category: Ouyang, J]] |
| - | [[Category: Parisini, E | + | [[Category: Parisini, E]] |
| - | [[Category: Reinherz, E L | + | [[Category: Reinherz, E L]] |
| - | [[Category: Tan, K | + | [[Category: Tan, K]] |
| - | [[Category: Wang, J H | + | [[Category: Wang, J H]] |
| - | [[Category: Wang, X | + | [[Category: Wang, X]] |
[[Category: Cd8aa]] | [[Category: Cd8aa]] | ||
[[Category: Cd8ab]] | [[Category: Cd8ab]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Mhc]] | [[Category: Mhc]] | ||
Revision as of 17:00, 24 December 2014
Crystal structure of a CD8ab heterodimer
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Categories: Mus musculus | Chang, H C | Le, Y | Liu, J H | Ouyang, J | Parisini, E | Reinherz, E L | Tan, K | Wang, J H | Wang, X | Cd8aa | Cd8ab | Immune system | Mhc
