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4qev

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qev OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qev RCSB], [http://www.ebi.ac.uk/pdbsum/4qev PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qev OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qev RCSB], [http://www.ebi.ac.uk/pdbsum/4qev PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baud, M.]]
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[[Category: Baud, M]]
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[[Category: Chirgadze, D Y.]]
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[[Category: Chirgadze, D Y]]
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[[Category: Ciulli, A.]]
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[[Category: Ciulli, A]]
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[[Category: Lin-Shiao, E.]]
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[[Category: Lin-Shiao, E]]
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[[Category: Tallant, C.]]
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[[Category: Tallant, C]]
[[Category: Bromodomain-containing protein 2]]
[[Category: Bromodomain-containing protein 2]]
[[Category: Kiaa9001]]
[[Category: Kiaa9001]]

Revision as of 17:04, 24 December 2014

Crystal structure of BRD2(BD2) mutant with ligand ME bound (METHYL (2R)- 2-[(4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4H-[1,2,4]TRIAZOLO[4,3-A][1, 4]BENZODIAZEPIN-4-YL]PROPANOATE)

4qev, resolution 1.80Å

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