1cgl
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cgl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cgl RCSB], [http://www.ebi.ac.uk/pdbsum/1cgl PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cgl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cgl RCSB], [http://www.ebi.ac.uk/pdbsum/1cgl PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MMP1_HUMAN MMP1_HUMAN]] Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.<ref>PMID:1645757</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 17:16, 24 December 2014
Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor
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