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4l0o
From Proteopedia
(Difference between revisions)
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| - | + | ==Structure determination of cystathionine gamma-synthase from Helicobacter pylori== | |
| - | === | + | <StructureSection load='4l0o' size='340' side='right' caption='[[4l0o]], [[Resolution|resolution]] 2.76Å' scene=''> |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4l0o]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L0O FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cystathionine gamma-synthase, HP_0106, metB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cystathionine_gamma-synthase Cystathionine gamma-synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.48 2.5.1.48] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l0o RCSB], [http://www.ebi.ac.uk/pdbsum/4l0o PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/METB_HELPY METB_HELPY]] Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity). | [[http://www.uniprot.org/uniprot/METB_HELPY METB_HELPY]] Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity). | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Campylobacter pylori]] |
[[Category: Cystathionine gamma-synthase]] | [[Category: Cystathionine gamma-synthase]] | ||
| - | [[Category: Gourinath, S | + | [[Category: Gourinath, S]] |
| - | [[Category: Rehman, S A.A | + | [[Category: Rehman, S A.A]] |
| - | [[Category: Tarique, K F | + | [[Category: Tarique, K F]] |
[[Category: C-s bond cleavage]] | [[Category: C-s bond cleavage]] | ||
[[Category: Elimination]] | [[Category: Elimination]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
Revision as of 17:20, 24 December 2014
Structure determination of cystathionine gamma-synthase from Helicobacter pylori
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