4m4c
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4m4c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M4C FirstGlance]. <br> | <table><tr><td colspan='2'>[[4m4c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M4C FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m4c RCSB], [http://www.ebi.ac.uk/pdbsum/4m4c PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m4c RCSB], [http://www.ebi.ac.uk/pdbsum/4m4c PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Chang, Y T | + | [[Category: Chang, Y T]] |
| - | [[Category: Chen, C Y | + | [[Category: Chen, C Y]] |
| - | [[Category: Chuang, W J | + | [[Category: Chuang, W J]] |
| - | [[Category: Jeng, W Y | + | [[Category: Jeng, W Y]] |
| - | [[Category: Shiu, J H | + | [[Category: Shiu, J H]] |
[[Category: Argdp]] | [[Category: Argdp]] | ||
[[Category: Disintegrin]] | [[Category: Disintegrin]] | ||
Revision as of 17:29, 24 December 2014
Crystal structure of Rhodostomin ARGDP mutant
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Categories: Chang, Y T | Chen, C Y | Chuang, W J | Jeng, W Y | Shiu, J H | Argdp | Disintegrin | Integrin | Loss-of-function | Rhodostomin | Toxin
