2xna

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<StructureSection load='2xna' size='340' side='right' caption='[[2xna]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2xna' size='340' side='right' caption='[[2xna]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xna]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNA OCA]. <br>
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<table><tr><td colspan='2'>[[2xna]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XNA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enf|1enf]], [[2esv|2esv]], [[1f77|1f77]], [[1qrn|1qrn]], [[1kgc|1kgc]], [[2bnr|2bnr]], [[2ak4|2ak4]], [[2gj6|2gj6]], [[2cdg|2cdg]], [[2bnu|2bnu]], [[2eys|2eys]], [[1mi5|1mi5]], [[2cdf|2cdf]], [[1fyt|1fyt]], [[1ymm|1ymm]], [[1ewc|1ewc]], [[1j8h|1j8h]], [[1zgl|1zgl]], [[2axh|2axh]], [[1ktk|1ktk]], [[2eyt|2eyt]], [[2bnq|2bnq]], [[1oga|1oga]], [[2eyr|2eyr]], [[2cde|2cde]], [[2xn9|2xn9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enf|1enf]], [[2esv|2esv]], [[1f77|1f77]], [[1qrn|1qrn]], [[1kgc|1kgc]], [[2bnr|2bnr]], [[2ak4|2ak4]], [[2gj6|2gj6]], [[2cdg|2cdg]], [[2bnu|2bnu]], [[2eys|2eys]], [[1mi5|1mi5]], [[2cdf|2cdf]], [[1fyt|1fyt]], [[1ymm|1ymm]], [[1ewc|1ewc]], [[1j8h|1j8h]], [[1zgl|1zgl]], [[2axh|2axh]], [[1ktk|1ktk]], [[2eyt|2eyt]], [[2bnq|2bnq]], [[1oga|1oga]], [[2eyr|2eyr]], [[2cde|2cde]], [[2xn9|2xn9]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xna RCSB], [http://www.ebi.ac.uk/pdbsum/2xna PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xna RCSB], [http://www.ebi.ac.uk/pdbsum/2xna PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ETXH_STAAU ETXH_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation.,Saline M, Rodstrom KE, Fischer G, Orekhov VY, Karlsson BG, Lindkvist-Petersson K Nat Commun. 2010 Nov 16;1:119. PMID:21081917<ref>PMID:21081917</ref>
The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation.,Saline M, Rodstrom KE, Fischer G, Orekhov VY, Karlsson BG, Lindkvist-Petersson K Nat Commun. 2010 Nov 16;1:119. PMID:21081917<ref>PMID:21081917</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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==See Also==
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*[[T-cell receptor|T-cell receptor]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Fischer, G.]]
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[[Category: Fischer, G]]
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[[Category: Karlsson, B G.]]
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[[Category: Karlsson, B G]]
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[[Category: Lindkvist-Petersson, K.]]
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[[Category: Lindkvist-Petersson, K]]
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[[Category: Orekhov, V Y.]]
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[[Category: Orekhov, V Y]]
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[[Category: Rodstrom, K E.J.]]
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[[Category: Rodstrom, K E.J]]
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[[Category: Saline, M.]]
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[[Category: Saline, M]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Superantigen]]
[[Category: Superantigen]]

Revision as of 17:31, 24 December 2014

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN T CELL RECEPTOR AND STAPHYLOCOCCAL ENTEROTOXIN

2xna, resolution 2.10Å

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