2xna
From Proteopedia
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| <StructureSection load='2xna' size='340' side='right' caption='[[2xna]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2xna' size='340' side='right' caption='[[2xna]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xna]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNA OCA]. <br> | + | <table><tr><td colspan='2'>[[2xna]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XNA FirstGlance]. <br> | 
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | 
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enf|1enf]], [[2esv|2esv]], [[1f77|1f77]], [[1qrn|1qrn]], [[1kgc|1kgc]], [[2bnr|2bnr]], [[2ak4|2ak4]], [[2gj6|2gj6]], [[2cdg|2cdg]], [[2bnu|2bnu]], [[2eys|2eys]], [[1mi5|1mi5]], [[2cdf|2cdf]], [[1fyt|1fyt]], [[1ymm|1ymm]], [[1ewc|1ewc]], [[1j8h|1j8h]], [[1zgl|1zgl]], [[2axh|2axh]], [[1ktk|1ktk]], [[2eyt|2eyt]], [[2bnq|2bnq]], [[1oga|1oga]], [[2eyr|2eyr]], [[2cde|2cde]], [[2xn9|2xn9]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enf|1enf]], [[2esv|2esv]], [[1f77|1f77]], [[1qrn|1qrn]], [[1kgc|1kgc]], [[2bnr|2bnr]], [[2ak4|2ak4]], [[2gj6|2gj6]], [[2cdg|2cdg]], [[2bnu|2bnu]], [[2eys|2eys]], [[1mi5|1mi5]], [[2cdf|2cdf]], [[1fyt|1fyt]], [[1ymm|1ymm]], [[1ewc|1ewc]], [[1j8h|1j8h]], [[1zgl|1zgl]], [[2axh|2axh]], [[1ktk|1ktk]], [[2eyt|2eyt]], [[2bnq|2bnq]], [[1oga|1oga]], [[2eyr|2eyr]], [[2cde|2cde]], [[2xn9|2xn9]]</td></tr> | 
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xna RCSB], [http://www.ebi.ac.uk/pdbsum/2xna PDBsum]</span></td></tr> | 
| - | + | </table> | |
| - | <table> | + | == Function == | 
| + | [[http://www.uniprot.org/uniprot/ETXH_STAAU ETXH_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.  | ||
| <div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| == Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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| The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation.,Saline M, Rodstrom KE, Fischer G, Orekhov VY, Karlsson BG, Lindkvist-Petersson K Nat Commun. 2010 Nov 16;1:119. PMID:21081917<ref>PMID:21081917</ref> | The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation.,Saline M, Rodstrom KE, Fischer G, Orekhov VY, Karlsson BG, Lindkvist-Petersson K Nat Commun. 2010 Nov 16;1:119. PMID:21081917<ref>PMID:21081917</ref> | ||
| - | From  | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | 
| </div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[T-cell receptor|T-cell receptor]] | ||
| == References == | == References == | ||
| <references/> | <references/> | ||
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| [[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| [[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Fischer, G | + | [[Category: Fischer, G]] | 
| - | [[Category: Karlsson, B G | + | [[Category: Karlsson, B G]] | 
| - | [[Category: Lindkvist-Petersson, K | + | [[Category: Lindkvist-Petersson, K]] | 
| - | [[Category: Orekhov, V Y | + | [[Category: Orekhov, V Y]] | 
| - | [[Category: Rodstrom, K E.J | + | [[Category: Rodstrom, K E.J]] | 
| - | [[Category: Saline, M | + | [[Category: Saline, M]] | 
| [[Category: Immune system]] | [[Category: Immune system]] | ||
| [[Category: Superantigen]] | [[Category: Superantigen]] | ||
Revision as of 17:31, 24 December 2014
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN T CELL RECEPTOR AND STAPHYLOCOCCAL ENTEROTOXIN
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