2uxy

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2uxy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UXY FirstGlance]. <br>
<table><tr><td colspan='2'>[[2uxy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UXY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C3Y:S-[(1S)-1-HYDROXY-1-(HYDROXYAMINO)ETHYL]-L-CYSTEINE'>C3Y</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C3Y:S-[(1S)-1-HYDROXY-1-(HYDROXYAMINO)ETHYL]-L-CYSTEINE'>C3Y</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k17|1k17]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k17|1k17]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uxy RCSB], [http://www.ebi.ac.uk/pdbsum/2uxy PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uxy RCSB], [http://www.ebi.ac.uk/pdbsum/2uxy PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AMIE_PSEAE AMIE_PSEAE]] Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia. Enables the organism to use acetamide as both carbon and nitrogen source.[HAMAP-Rule:MF_01242] Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates (By similarity).[HAMAP-Rule:MF_01242]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Amidase]]
[[Category: Amidase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Andrade, J.]]
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[[Category: Andrade, J]]
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[[Category: Carrondo, M A.]]
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[[Category: Carrondo, M A]]
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[[Category: Frazao, C.]]
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[[Category: Frazao, C]]
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[[Category: Karmali, A.]]
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[[Category: Karmali, A]]
[[Category: Acyl transfer]]
[[Category: Acyl transfer]]
[[Category: Aliphatic amidase]]
[[Category: Aliphatic amidase]]
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[[Category: Hydroxamic acid]]
[[Category: Hydroxamic acid]]
[[Category: Nitrilase superfamily]]
[[Category: Nitrilase superfamily]]
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[[Category: Pseudomonas aeruginosa]]
 
[[Category: Thiol enzyme]]
[[Category: Thiol enzyme]]

Revision as of 17:35, 24 December 2014

ALIPHATIC AMIDASE

2uxy, resolution 1.25Å

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