3b6k

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3b6k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B6K FirstGlance]. <br>
<table><tr><td colspan='2'>[[3b6k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B6K FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PLQ:1,4-BENZOQUINONE'>PLQ</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PLQ:1,4-BENZOQUINONE'>PLQ</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b6i|3b6i]], [[3b6j|3b6j]], [[3b6m|3b6m]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b6i|3b6i]], [[3b6j|3b6j]], [[3b6m|3b6m]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b6k RCSB], [http://www.ebi.ac.uk/pdbsum/3b6k PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b6k RCSB], [http://www.ebi.ac.uk/pdbsum/3b6k PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/WRBA_ECOLI WRBA_ECOLI]] It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH.<ref>PMID:9694845</ref> <ref>PMID:16672604</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Andrade, S L.A.]]
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[[Category: Andrade, S L.A]]
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[[Category: Einsle, O.]]
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[[Category: Einsle, O]]
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[[Category: Ferry, J G.]]
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[[Category: Ferry, J G]]
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[[Category: Patridge, E V.]]
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[[Category: Patridge, E V]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Fmn]]
[[Category: Nadh:quinone oxidoreductase]]
[[Category: Nadh:quinone oxidoreductase]]

Revision as of 17:45, 24 December 2014

WrbA from Escherichia coli, Benzoquinone complex

3b6k, resolution 1.99Å

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