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1md6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1md6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MD6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1md6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MD6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1md6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1md6 RCSB], [http://www.ebi.ac.uk/pdbsum/1md6 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1md6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1md6 RCSB], [http://www.ebi.ac.uk/pdbsum/1md6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/I36RA_MOUSE I36RA_MOUSE]] Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Dunn, E F | + | [[Category: Dunn, E F]] |
| - | [[Category: Gay, N J | + | [[Category: Gay, N J]] |
| - | [[Category: Neill, L A.O | + | [[Category: Neill, L A.O]] |
| - | [[Category: Pei, X Y | + | [[Category: Pei, X Y]] |
[[Category: Alpha helix]] | [[Category: Alpha helix]] | ||
[[Category: Beta triple]] | [[Category: Beta triple]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
Revision as of 17:45, 24 December 2014
High resolution crystal structure of murine IL-1F5 reveals unique loop conformation for specificity
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