This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3rnj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3rnj.png|left|200px]]
+
==Crystal structure of the SH3 domain from IRSp53 (BAIAP2)==
-
 
+
<StructureSection load='3rnj' size='340' side='right' caption='[[3rnj]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
{{STRUCTURE_3rnj| PDB=3rnj | SCENE= }}
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3rnj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RNJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RNJ FirstGlance]. <br>
-
===Crystal structure of the SH3 domain from IRSp53 (BAIAP2)===
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EDT:{[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC+ACID'>EDT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAIAP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rnj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rnj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rnj RCSB], [http://www.ebi.ac.uk/pdbsum/3rnj PDBsum]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[3rnj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RNJ OCA].
+
== Function ==
 +
[[http://www.uniprot.org/uniprot/BAIP2_HUMAN BAIP2_HUMAN]] Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.<ref>PMID:11130076</ref> <ref>PMID:11696321</ref> <ref>PMID:14752106</ref> <ref>PMID:19366662</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith, C H]]
-
[[Category: Barilari, M.]]
+
[[Category: Barilari, M]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra, C]]
-
[[Category: Chaikuad, A.]]
+
[[Category: Chaikuad, A]]
-
[[Category: Delft, F von.]]
+
[[Category: Delft, F von]]
-
[[Category: Dente, L.]]
+
[[Category: Dente, L]]
[[Category: Edwards, A M]]
[[Category: Edwards, A M]]
-
[[Category: Feller, S M.]]
+
[[Category: Feller, S M]]
-
[[Category: Filippakopoulos, P.]]
+
[[Category: Filippakopoulos, P]]
-
[[Category: Knapp, S.]]
+
[[Category: Knapp, S]]
-
[[Category: Muniz, J R.C.]]
+
[[Category: Muniz, J R.C]]
-
[[Category: Raynor, J.]]
+
[[Category: Raynor, J]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Structural genomic]]
-
[[Category: Simister, P C.]]
+
[[Category: Simister, P C]]
-
[[Category: Tregubova, A.]]
+
[[Category: Tregubova, A]]
-
[[Category: Vollmar, M.]]
+
[[Category: Vollmar, M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt, J]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Proline-rich motif]]
[[Category: Proline-rich motif]]
Line 31: Line 36:
[[Category: Protein interaction domain]]
[[Category: Protein interaction domain]]
[[Category: Sgc]]
[[Category: Sgc]]
-
[[Category: Structural genomic]]
 
-
[[Category: Structural genomics consortium]]
 

Revision as of 17:46, 24 December 2014

Crystal structure of the SH3 domain from IRSp53 (BAIAP2)

3rnj, resolution 1.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3rnj"
Personal tools