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3oq3
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3oq3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ectromelia_virus Ectromelia virus] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OQ3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3oq3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ectromelia_virus Ectromelia virus] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OQ3 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ifna5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), C12R, EVM166 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12643 Ectromelia virus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ifna5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), C12R, EVM166 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12643 Ectromelia virus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oq3 RCSB], [http://www.ebi.ac.uk/pdbsum/3oq3 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oq3 RCSB], [http://www.ebi.ac.uk/pdbsum/3oq3 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IFNA5_MOUSE IFNA5_MOUSE]] Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. | ||
==See Also== | ==See Also== | ||
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[[Category: Ectromelia virus]] | [[Category: Ectromelia virus]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Fremont, D H | + | [[Category: Fremont, D H]] |
| - | [[Category: Lee, C A | + | [[Category: Lee, C A]] |
| - | + | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Cytokine decoy receptor]] | [[Category: Cytokine decoy receptor]] | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Soluble a/b-ifnr]] | [[Category: Soluble a/b-ifnr]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Type-1 interferon]] | [[Category: Type-1 interferon]] | ||
[[Category: Viral immune evasion]] | [[Category: Viral immune evasion]] | ||
[[Category: Virus/viral protein]] | [[Category: Virus/viral protein]] | ||
Revision as of 17:50, 24 December 2014
Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
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Categories: Ectromelia virus | Mus musculus | Structural genomic | Fremont, D H | Lee, C A | Csgid | Cytokine decoy receptor | Cytokine-viral protein complex | Ectromelia | Extracellular | Ifn-alpha | Ifn-alpha/beta binding protein | Immunoglobulin domain | Immunoglobulin-like | Moscow strain | Mousepox virus | Secreted | Soluble a/b-ifnr | Type-1 interferon | Viral immune evasion | Virus/viral protein
