3gmh

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gmh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gmh RCSB], [http://www.ebi.ac.uk/pdbsum/3gmh PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gmh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gmh RCSB], [http://www.ebi.ac.uk/pdbsum/3gmh PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MD2L1_HUMAN MD2L1_HUMAN]] Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.<ref>PMID:10700282</ref> <ref>PMID:11804586</ref> <ref>PMID:15024386</ref>
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== References ==
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<references/>
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</StructureSection>
</StructureSection>

Revision as of 17:59, 24 December 2014

Crystal Structure of the Mad2 Dimer

3gmh, resolution 3.95Å

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