3q2h
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2h RCSB], [http://www.ebi.ac.uk/pdbsum/3q2h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2h RCSB], [http://www.ebi.ac.uk/pdbsum/3q2h PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ATS1_HUMAN ATS1_HUMAN]] Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.<ref>PMID:10438512</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 18:17, 24 December 2014
Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4
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