This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3psn
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [http://www.ebi.ac.uk/pdbsum/3psn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [http://www.ebi.ac.uk/pdbsum/3psn PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 18:28, 24 December 2014
Crystal structure of mouse VPS29 complexed with Mn2+
| |||||||||||
Categories: Mus musculus | Phosphoserine phosphatase | Chhabra, S | Collins, B | Ghai, R | Norwood, S | Shaw, D | Swarbrick, J | Valkov, E | Hydrolase | Membrane trafficking | Phosphtase fold | Scaffolding | Snx1 | Tbc1d5 | Vps35
