4o38
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o38 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o38 RCSB], [http://www.ebi.ac.uk/pdbsum/4o38 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o38 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o38 RCSB], [http://www.ebi.ac.uk/pdbsum/4o38 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GAK_HUMAN GAK_HUMAN]] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.<ref>PMID:10625686</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 18:30, 24 December 2014
Crystal structure of the human cyclin G associated kinase (GAK)
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Categories: Human | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Chaikuad, A | Delft, F von | Edwards, A | Eswaran, J | Fedorov, O | Hatzos-Skintges, C | Joachimiak, A | King, O | Knapp, S | Structural genomic | Weger, A | Weigelt, J | Zhang, R | Atp-binding | Cell cycle | Cell junction | Clathrine | Cyclin g | Golgi apparatus | Kinase | Mcsg | Membrane trafficking | Nucleotide-binding | P53 | Phosphoprotein | Protein kinase | PSI, Protein structure initiative | Serine/threonine kinase | Sgc | Transferase
