1x45

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1x45]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X45 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1x45]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X45 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1, MINT1, X11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1, MINT1, X11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x45 RCSB], [http://www.ebi.ac.uk/pdbsum/1x45 PDBsum], [http://www.topsan.org/Proteins/RSGI/1x45 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x45 RCSB], [http://www.ebi.ac.uk/pdbsum/1x45 PDBsum], [http://www.topsan.org/Proteins/RSGI/1x45 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/APBA1_HUMAN APBA1_HUMAN]] Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi, F]]
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[[Category: Qin, X R.]]
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[[Category: Qin, X R]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Adapter protein xii alpha]]
[[Category: Adapter protein xii alpha]]
[[Category: Amyloid beta a4 precursor protein-binding family some]]
[[Category: Amyloid beta a4 precursor protein-binding family some]]
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[[Category: Nppsfa]]
[[Category: Nppsfa]]
[[Category: Pdz domain]]
[[Category: Pdz domain]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 

Revision as of 18:31, 24 December 2014

Solution structure of the first PDZ domain of amyloid beta A4 precursor protein-binding family A, member 1

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