1uhn

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uhn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UHN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uhn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UHN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aui|1aui]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aui|1aui]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uhn RCSB], [http://www.ebi.ac.uk/pdbsum/1uhn PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uhn RCSB], [http://www.ebi.ac.uk/pdbsum/1uhn PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CNBL2_ARATH CNBL2_ARATH]] Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Binds four calcium ions per subunit. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Mediates the inactivation of the proton pump AHA2 by CIPK11. Probably involved in regulating signaling responses to abscisic acid.<ref>PMID:17483306</ref> <ref>PMID:17898163</ref> <ref>PMID:22547024</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Hashimoto, H.]]
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[[Category: Hashimoto, H]]
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[[Category: Koizumi, N.]]
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[[Category: Koizumi, N]]
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[[Category: Nagae, M.]]
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[[Category: Nagae, M]]
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[[Category: Nozawa, A.]]
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[[Category: Nozawa, A]]
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[[Category: Sano, H.]]
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[[Category: Sano, H]]
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[[Category: Sato, M.]]
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[[Category: Sato, M]]
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[[Category: Shimizu, T.]]
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[[Category: Shimizu, T]]
[[Category: Calcium binding protein]]
[[Category: Calcium binding protein]]
[[Category: Metal binding protein]]
[[Category: Metal binding protein]]

Revision as of 18:35, 24 December 2014

The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana

1uhn, resolution 2.10Å

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