1ytb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1ytb.jpg|left|200px]]<br /><applet load="1ytb" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1ytb.jpg|left|200px]]
-
caption="1ytb, resolution 1.800&Aring;" />
+
 
-
'''CRYSTAL STRUCTURE OF A YEAST TBP/TATA-BOX COMPLEX'''<br />
+
{{Structure
 +
|PDB= 1ytb |SIZE=350|CAPTION= <scene name='initialview01'>1ytb</scene>, resolution 1.800&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''CRYSTAL STRUCTURE OF A YEAST TBP/TATA-BOX COMPLEX'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1YTB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTB with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTB OCA].
+
1YTB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTB with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTB OCA].
==Reference==
==Reference==
-
Crystal structure of a yeast TBP/TATA-box complex., Kim Y, Geiger JH, Hahn S, Sigler PB, Nature. 1993 Oct 7;365(6446):512-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8413604 8413604]
+
Crystal structure of a yeast TBP/TATA-box complex., Kim Y, Geiger JH, Hahn S, Sigler PB, Nature. 1993 Oct 7;365(6446):512-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8413604 8413604]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 20: Line 29:
[[Category: protein-dna complex]]
[[Category: protein-dna complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:08:55 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:27:14 2008''

Revision as of 13:27, 20 March 2008

Image:1ytb.jpg


PDB ID 1ytb

Drag the structure with the mouse to rotate
, resolution 1.800Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A YEAST TBP/TATA-BOX COMPLEX


Overview

The 2.5 A crystal structure of a TATA-box complex with yeast TBP shows that the eight base pairs of the TATA box bind to the concave surface of TBP by bending towards the major groove with unprecedented severity. This produces a wide open, underwound, shallow minor groove which forms a primarily hydrophobic interface with the entire under-surface of the TBP saddle. The severe bend and a positive writhe radically alter the trajectory of the flanking B-form DNA.

About this Structure

1YTB is a Single protein structure of sequence from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTB with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Reference

Crystal structure of a yeast TBP/TATA-box complex., Kim Y, Geiger JH, Hahn S, Sigler PB, Nature. 1993 Oct 7;365(6446):512-20. PMID:8413604

Page seeded by OCA on Thu Mar 20 15:27:14 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ytb"
Personal tools