1koe
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1koe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KOE FirstGlance]. <br> | <table><tr><td colspan='2'>[[1koe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KOE FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1koe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1koe RCSB], [http://www.ebi.ac.uk/pdbsum/1koe PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1koe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1koe RCSB], [http://www.ebi.ac.uk/pdbsum/1koe PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/COIA1_MOUSE COIA1_MOUSE]] Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Hohenester, E | + | [[Category: Hohenester, E]] |
| - | [[Category: Olsen, B R | + | [[Category: Olsen, B R]] |
| - | [[Category: Sasaki, T | + | [[Category: Sasaki, T]] |
| - | [[Category: Timpl, R | + | [[Category: Timpl, R]] |
[[Category: Angiogenesis inhibitor]] | [[Category: Angiogenesis inhibitor]] | ||
[[Category: Collagen xviii]] | [[Category: Collagen xviii]] | ||
[[Category: Heparin-binding domain]] | [[Category: Heparin-binding domain]] | ||
[[Category: Non-collageneous domain]] | [[Category: Non-collageneous domain]] | ||
Revision as of 18:38, 24 December 2014
ENDOSTATIN
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