3zhg

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<StructureSection load='3zhg' size='340' side='right' caption='[[3zhg]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='3zhg' size='340' side='right' caption='[[3zhg]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zhg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZHG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zhg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZHG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zg5|3zg5]], [[3zh3|3zh3]], [[3zh4|3zh4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zg5|3zg5]], [[3zh3|3zh3]], [[3zh4|3zh4]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zhg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zhg RCSB], [http://www.ebi.ac.uk/pdbsum/3zhg PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zhg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zhg RCSB], [http://www.ebi.ac.uk/pdbsum/3zhg PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/C209B_MOUSE C209B_MOUSE]] Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
[[Category: Bartual, S G]]
[[Category: Bartual, S G]]
[[Category: Hermoso, J A]]
[[Category: Hermoso, J A]]

Revision as of 18:40, 24 December 2014

Crystallographic structure of the native mouse SIGN-R1 CRD domain

3zhg, resolution 1.87Å

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