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3b7g

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3b7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B7G FirstGlance]. <br>
<table><tr><td colspan='2'>[[3b7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B7G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oxc|2oxc]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oxc|2oxc]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDX20, DP103, GEMIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDX20, DP103, GEMIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b7g RCSB], [http://www.ebi.ac.uk/pdbsum/3b7g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b7g RCSB], [http://www.ebi.ac.uk/pdbsum/3b7g PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DDX20_HUMAN DDX20_HUMAN]] The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berg, S Van Den.]]
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[[Category: Berg, S Van Den]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Busam, R D.]]
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[[Category: Busam, R D]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Dahlgren, L G.]]
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[[Category: Dahlgren, L G]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Holmberg-Schiavone, L.]]
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[[Category: Holmberg-Schiavone, L]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Kallas, A.]]
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[[Category: Kallas, A]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova, T]]
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[[Category: Lehtio, L.]]
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[[Category: Lehtio, L]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nilsson, M E.]]
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[[Category: Nilsson, M E]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Sagemark, J.]]
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[[Category: Sagemark, J]]
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[[Category: Svensson, L.]]
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[[Category: Svensson, L]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L.]]
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[[Category: Tresaugues, L]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M.]]
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[[Category: Welin, M]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Conserved domain i]]
[[Category: Conserved domain i]]
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[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Spliceosome]]
[[Category: Spliceosome]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 

Revision as of 18:45, 24 December 2014

Human DEAD-box RNA helicase DDX20, Conserved domain I (DEAD) in complex with AMPPNP (Adenosine-(Beta,gamma)-imidotriphosphate)

3b7g, resolution 1.90Å

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OCA

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